3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins. GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Clinical toxicity of Acetaminophen A) The CID pathways of N acetyl p benzoquinone imine glutathione Download Scientific Diagram Paracetamol (Acetaminophen) Poisoning: NAPQI Metabolite, Glutathione and Antidote (NSAIDs) YouTube Deleterious Effects of Reactive Metabolites
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glutathione napqi Metabolic pathway for NAPQI formation and detoxification by conjugation...