Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Oral Melanotic Macule: Symptoms and Treatment Skinsight Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Labial melanotic macule (brown spot on lip) (Stony Brook Case 1) dermatology dermatopathology This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding