Problem 2: N acetyl para benzoquinone (NAPQI) is an oxidized metabolite of acetaminophen formed in the liver. NAPQI is converted into an acetaminophen glutathione conjugate, a non toxic metabolite Unveiling the molecular basis of paracetamol induced hepatotoxicity: Interaction of N acetyl p benzoquinone imine with mitochondrial succinate dehydrogenase ScienceDirect Acute acetaminophen paracetamol toxicity Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine YouTube Why patients taking enzyme Inducers and patients with anorexia nervosa experience higher risk of paracetamol toxicity?? Acetaminophen (Paracetamol) is extensively metabolized by the liver via three main hepatic pathways: glucuronidation, sulfation, NAPQI an overview ScienceDirect Topics