N Acetyl 4 benzoquinone imine (NAPQI, N Acetyl p benzoquinonimine, CAS Number: 50700 49 7) Cayman Chemical Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Acetaminophen Pathway (toxic doses), Pharmacokinetics An Example of a Drug That Causes Toxicity Through the Formation of a Chemically Reactive Intermediate Mechanisms of Adverse Drug Reactions Pharmacovigilance Full article: The acetaminophen metabolite N acetyl p benzoquinone imine ( NAPQI) inhibits glutathione synthetase in vitro; a clue to the mechanism of 5 oxoprolinuric acidosis? Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body