Sex differences in glutathione metabolism and acetaminophen toxicity Acetaminophen (brand name Tylenol) is found in hundreds of prescription and over the counter medicines. Taking more than directed can cause serious health problems. Always read medicine labels and follow the instructions carefully. If OTC, NOT RISK FREE: We're getting more calls than usual about acetaminophen, the active ingredient in Tylenol. Many over the counter (OTC) products contain a mix of pain and fever reducers, cough suppressants, and other Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury Vliegenthart 2017 Clinical Pharmacology & Therapeutics Wiley Online Library g glutamyl cycle. Depletion of glutathione by acetaminophen leads to Download Scientific Diagram Liberation of daidzein by gut microbial galactosidase suppresses acetaminophen induced hepatotoxicity in mice: Cell Host & Microbe