Sex differences in glutathione metabolism and acetaminophen toxicity Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Figure 1: CMAJ Biochemistry Metabolism of acetaminophen (paracetamol) . Acetaminophen is widely used as a painkiller. Taken in the usual therapeutic doses, it is Instagram Researchers are studying a possible link between acetaminophen (Tylenol) use during pregnancy and higher autism or ADHD risk. It may lower glutathione, an important antioxidant for brain development. Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins &